Liotrix

Liotrix
Combination of
Thyroxine	Thyroid hormone
Triiodothyronine	Thyroid hormone
Clinical data
Trade names	Thyrolar
AHFS/Drugs.com	Multum Consumer Information
Routes of; administration	Oral
ATC code	H03AA03 (WHO) ;
Legal status
Legal status	US: ℞-only;
Identifiers
CAS Number	8065-29-0 ;
PubChem CID	165686;
DrugBank	DB01583;
ChemSpider	none;
UNII	YW8HJ0N26X;
KEGG	D00361;
CompTox Dashboard (EPA)	DTXSID401001390 ;

Liotrix is a 4:1 mixture of thyroxine (T₄) and triiodothyronine (T₃) made synthetically. It is used to replenish thyroid hormones in thyroid deficiency and hypothyroidism. The only brand of liotrix available in the U.S. is Thyrolar, manufactured by Forest Laboratories.

Sometime prior to 2008 Forest Laboratories released the following statement regarding the limited availability of liotrix: "U.S. Pharmacopeia, an official public standards-setting authority for prescription and over-the-counter medicines and other health care products manufactured or sold in the United States, has mandated new specifications for a component used in the manufacturing of Thyrolar. As a result, all strengths of Thyrolar are currently on long-term back order while modifications necessary to meet these new specifications are made."^[1]

^ "Thyrolar". Forest Pharmaceuticals, Inc. Archived from the original on 11 August 2008.

[1] "Thyrolar". Forest Pharmaceuticals, Inc. Archived from the original on 11 August 2008.

[1]