1959 12 Hours of Sebring

The 1959 12-Hour Florida International Grand Prix of Endurance for the Amoco Trophy was a motor race for sportscars, staged on 21 March at the Sebring International Raceway, Florida, United States. It was the opening round of the 1959 World Sportscar Championship and was the eighth running of the 12 Hours of Sebring.

The race was won by Dan Gurney, Phil Hill, Chuck Daigh and Olivier Gendebien driving a Ferrari 250 TR 59 for Scuderia Ferrari.