Trump won Missouri again by a 15.4% margin. This was 3.1% lower than his 2016 margin, but still a better performance in the state than that of any other Republican nominee since Ronald Reagan in 1984. Prior to the election, most news organizations considered this a state Trump would win; during the 21st century Missouri has shifted away from being one of the most notable bellwether states towards becoming a reliably red state. Trump became the first incumbent president since Grover Cleveland in 1888 to win Missouri and lose re-election and the first-ever Republican incumbent to do so. This is also the first time since 1916 (and only the second time ever) that Missouri has voted more Republican than neighboring Kansas.
In this election, Missouri voted just under 20% to the right of the nation as a whole.