Antiprogestogen | |
---|---|
Drug class | |
Class identifiers | |
Synonyms | Antiprogestins; Progesterone antagonists; Progesterone blockers |
Use | Medical abortion, emergency contraception, uterine fibroids |
ATC code | G03XB |
Biological target | Progesterone receptor |
Chemical class | Steroidal |
Legal status | |
In Wikidata |
Antiprogestogens or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body. These drugs competitively inhibit progestin at progesterone receptors, acting by blocking the progesterone receptor (PR) and/or inhibiting or suppressing progestogen production. Antiprogestogens are one of three types of sex hormone antagonists, alongside antiestrogens and antiandrogens.[1]