Antiprogestogen

Antiprogestogen
Drug class
Mifepristone, an antiprogestogen that is used to induce medical abortions.
Class identifiers
SynonymsAntiprogestins; Progesterone antagonists; Progesterone blockers
UseMedical abortion, emergency contraception, uterine fibroids
ATC codeG03XB
Biological targetProgesterone receptor
Chemical classSteroidal
Legal status
In Wikidata

Antiprogestogens or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body. These drugs competitively inhibit progestin at progesterone receptors, acting by blocking the progesterone receptor (PR) and/or inhibiting or suppressing progestogen production. Antiprogestogens are one of three types of sex hormone antagonists, alongside antiestrogens and antiandrogens.[1]

  1. ^ Nath JL (2006). Using Medical Terminology: A Practical Approach. Lippincott Williams & Wilkins. pp. 977–. ISBN 978-0-7817-4868-1.

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