Apicoplast

An apicoplast is a derived non-photosynthetic plastid found in most Apicomplexa, including Toxoplasma gondii, and Plasmodium falciparum and other Plasmodium spp. (parasites causing malaria), but not in others such as Cryptosporidium. It originated from algae through secondary endosymbiosis; there is debate as to whether this was a green or red alga. The apicoplast is surrounded by four membranes within the outermost part of the endomembrane system.[1] The apicoplast hosts important metabolic pathways like fatty acid synthesis, isoprenoid precursor synthesis and parts of the heme biosynthetic pathway.[2]

  1. ^ Lim L, McFadden GI (March 2010). "The evolution, metabolism and functions of the apicoplast". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365 (1541): 749–63. doi:10.1098/rstb.2009.0273. PMC 2817234. PMID 20124342.
  2. ^ Sheiner L, Vaidya AB, McFadden GI (August 2013). "The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp". Current Opinion in Microbiology. 16 (4): 452–8. doi:10.1016/j.mib.2013.07.003. PMC 3767399. PMID 23927894.

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