Bone scintigraphy

Bone scintigraphy
A nuclear medicine whole-body bone scan. The nuclear medicine whole-body bone scan is generally used in evaluations of various bone-related pathology, such as for bone pain, stress fracture, nonmalignant bone lesions, bone infections, or the spread of cancer to the bone.
ICD-9-CM92.14
OPS-301 code3-705
MedlinePlus003833

A bone scan or bone scintigraphy /sɪnˈtɪɡrəfi/ is a nuclear medicine imaging technique of the bone. It can help diagnose a number of bone conditions, including cancer of the bone or metastasis, location of bone inflammation and fractures (that may not be visible in traditional X-ray images), and bone infection (osteomyelitis).[1]

Nuclear medicine provides functional imaging and allows visualisation of bone metabolism or bone remodeling, which most other imaging techniques (such as X-ray computed tomography, CT) cannot.[2][3] Bone scintigraphy competes with positron emission tomography (PET) for imaging of abnormal metabolism in bones, but is considerably less expensive.[4] Bone scintigraphy has higher sensitivity but lower specificity than CT or MRI for diagnosis of scaphoid fractures following negative plain radiography.[5]

  1. ^ Bahk, Yong-Whee (2000). Combined scintigraphic and radiographic diagnosis of bone and joint diseases (2nd ed.). Berlin, Heidelberg: Springer. p. 3. ISBN 9783662041062.
  2. ^ Ćwikła, Jarosław B. (2013). "New imaging techniques in reumathology: MRI, scintigraphy and PET". Polish Journal of Radiology. 78 (3): 48–56. doi:10.12659/PJR.889138. PMC 3789933. PMID 24115960.
  3. ^ Livieratos, Lefteris (2012). "Basic Principles of SPECT and PET Imaging". In Fogelman, Ignac; Gnanasegaran, Gopinath; van der Wall, Hans (eds.). Radionuclide and Hybrid Bone Imaging. Berlin: Springer. p. 345. doi:10.1007/978-3-642-02400-9_12. ISBN 978-3-642-02399-6.
  4. ^ O'Sullivan, Gerard J (2015). "Imaging of bone metastasis: An update". World Journal of Radiology. 7 (8): 202–11. doi:10.4329/wjr.v7.i8.202. PMC 4553252. PMID 26339464.
  5. ^ Mallee, WH; Wang, J; Poolman, RW; Kloen, P; Maas, M; de Vet, HC; Doornberg, JN (5 June 2015). "Computed tomography versus magnetic resonance imaging versus bone scintigraphy for clinically suspected scaphoid fractures in patients with negative plain radiographs". The Cochrane Database of Systematic Reviews. 2015 (6): CD010023. doi:10.1002/14651858.CD010023.pub2. PMC 6464799. PMID 26045406.

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