Custom peptide synthesis

Solid phase peptide synthesis

Custom peptide synthesis is the commercial production of peptides for use in biochemistry, biology, biotechnology, pharmacology and molecular medicine.[1] Custom peptide synthesis provides synthetic peptides as valuable tools to biomedical laboratories. Synthetic oligopeptides are used extensively in research for structure-function analysis (for example to study protein-protein interfaces), for the development of binding assays, the study of receptor agonist/antagonists or as immunogens for the production of specific antibodies. Generally, peptides are synthesized by coupling the carboxyl group or C-terminus of one amino acid to the amino group or N-terminus of another using automated solid phase peptide synthesis chemistries. However, liquid phase synthesis may also be used for specific needs.[2]

  1. ^ Stawikowski, M.; Fields, G. B. (5 February 2013). "Introduction to Peptide Synthesis". Current Protocols in Protein Science. CHAPTER: Unit-18.1. doi:10.1002/0471140864.ps1801s26. PMC 3564544. PMID 18429226.
  2. ^ "Peptide Synthesis - How peptides are made". Retrieved 2024-01-21.

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