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Fatigue

This article is about the medical term. For other uses, see Fatigue (disambiguation).
Not to be confused with Muscle weakness or Lethargy.

Fatigue
Other namesExhaustion, weariness, tiredness, lethargy, listlessness
Artistic representation of ME/CFS
SpecialtyPrimary care Edit this on Wikidata
TreatmentAvoid known stressors and unhealthy habits (drug use, excessive alcohol consumption, smoking), healthy diet, exercise regularly, medication, hydration, and vitamins

Fatigue describes a state of tiredness (which is not sleepiness), exhaustion[1] or loss of energy.[2][3]

Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases, and post-infectious-disease states.[4] However, fatigue is complex and in up to a third of primary care cases no medical or psychiatric diagnosis is found.[5][6][7]

Fatigue (in the general usage sense of normal tiredness) often follows prolonged physical or mental activity. Physical fatigue results from muscle fatigue brought about by intense physical activity.[8][9][10] Mental fatigue results from prolonged periods of cognitive activity which impairs cognitive ability, can manifest as sleepiness, lethargy, or directed attention fatigue,[11] and can also impair physical performance.[12]

  1. ^ "10 medical reasons for feeling tired". nhs.uk. 3 October 2018. Archived from the original on 24 November 2021. Retrieved 24 November 2021.
  2. ^ "Fatigue". Mayo Clinic. Archived from the original on 2023-01-06. Retrieved 2023-01-06.
  3. ^ "Cancer terms". Archived from the original on 2023-01-06. Retrieved 2023-01-06.
  4. ^ Finsterer J, Mahjoub SZ (August 2014). "Fatigue in healthy and diseased individuals". Am J Hosp Palliat Care. 31 (5): 562–575. doi:10.1177/1049909113494748. PMID 23892338. S2CID 12582944.
  5. ^ Cite error: The named reference BMJ-Best-Practice-2023 was invoked but never defined (see the help page).
  6. ^ "Medically unexplained symptoms". 19 October 2017. Archived from the original on 29 September 2017. Retrieved 6 January 2023.
  7. ^ Haß U, Herpich C, Norman K (September 2019). "Anti-Inflammatory Diets and Fatigue". Nutrients. 11 (10): 2315. doi:10.3390/nu11102315. PMC 6835556. PMID 31574939.
  8. ^ Gandevia SC (February 1992). "Some central and peripheral factors affecting human motoneuronal output in neuromuscular fatigue". Sports Medicine. 13 (2): 93–98. doi:10.2165/00007256-199213020-00004. PMID 1561512. S2CID 20473830.
  9. ^ Hagberg M (July 1981). "Muscular endurance and surface electromyogram in isometric and dynamic exercise". Journal of Applied Physiology. 51 (1): 1–7. doi:10.1152/jappl.1981.51.1.1. PMID 7263402.
  10. ^ Hawley JA, Reilly T (June 1997). "Fatigue revisited". Journal of Sports Sciences. 15 (3): 245–246. doi:10.1080/026404197367245. PMID 9232549.
  11. ^ Marcora SM, Staiano W, Manning V (March 2009). "Mental fatigue impairs physical performance in humans". Journal of Applied Physiology. 106 (3): 857–864. CiteSeerX 10.1.1.557.3566. doi:10.1152/japplphysiol.91324.2008. PMID 19131473. S2CID 12221961.
  12. ^ Martin K, Meeusen R, Thompson KG, Keegan R, Rattray B (September 2018). "Mental Fatigue Impairs Endurance Performance: A Physiological Explanation". Sports Med. 48 (9): 2041–2051. doi:10.1007/s40279-018-0946-9. PMID 29923147. S2CID 49317682.

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