Genetically modified fish

Genetically modified fish (GM fish) are organisms from the taxonomic clade which includes the classes Agnatha (jawless fish), Chondrichthyes (cartilaginous fish) and Osteichthyes (bony fish) whose genetic material (DNA) has been altered using genetic engineering techniques. In most cases, the aim is to introduce a new trait to the fish which does not occur naturally in the species, i.e. transgenesis.

GM fish are used in scientific research and kept as pets. They are being developed as environmental pollutant sentinels and for use in aquaculture food production. In 2015, the AquAdvantage salmon was approved by the US Food and Drug Administration (FDA) for commercial production, sale and consumption,[1] making it the first genetically modified animal to be approved for human consumption. Some GM fish that have been created have promoters driving an over-production of "all fish" growth hormone. This results in dramatic growth enhancement in several species, including salmonids,[2] carps[3] and tilapias.[4][5]

Critics have objected to GM fish on several grounds, including ecological concerns, animal welfare concerns and with respect to whether using them as food is safe and whether GM fish are needed to help address the world's food needs.

  1. ^ Staff (November 2015)FDA Has Determined That the AquAdvantage Salmon is as Safe to Eat as Non-GE Salmon FDA Consumer Health Information / U.S. Food and Drug Administration / November 2015 / Retrieved 20 November 2015
  2. ^ Jun Du, Shao; Zhiyuan Gong, Garth L. Fletcher, Margaret A. Shears, Madonna J. King, David R. Idler & Choy L. Hew (1992). "Growth Enhancement in Transgenic Atlantic Salmon by the Use of an "All Fish" Chimeric Growth Hormone Gene Construct". Bio/Technology. 10 (2): 176–181. doi:10.1038/nbt0292-176. PMID 1368229. S2CID 27048646.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Devlin, Robert; Carlo A. Biagi, Timothy Y. Yesaki, Duane E. Smailus & John C. Byatt (15 February 2001). "Growth of domesticated transgenic fish". Nature. 409 (6822): 781–782. Bibcode:2001Natur.409..781D. doi:10.1038/35057314. PMID 11236982. S2CID 5293883.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Rahman, M. A.; A. Ronyai, B. Z. Engidaw, K.Jauncey, G-L. Hwang, A. Smith, E. Roderick, D.Penman, L.Varadi, N. Maclean (19 April 2005). "Growth and nutritional trials on transgenic Nile tilapia containing an exogenous fish growth hormone gene". Journal of Fish Biology. 59 (1): 62–78. doi:10.1111/j.1095-8649.2001.tb02338.x. Archived from the original on 5 January 2013. Retrieved 28 May 2009.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  5. ^ Hackett P.B., Alvarez M.C. (2000). "The molecular genetics of transgenic fish". Recent Adv. Mar. Biotech. 4: 77–145.

Developed by StudentB