GroES

HSPE1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4PJ1
Identifiers
Aliases	HSPE1, heat shock 10kDa protein 1, CPN10, EPF, GROES, HSP10, heat shock protein family E (Hsp10) member 1
External IDs	OMIM: 600141; MGI: 104680; HomoloGene: 20500; GeneCards: HSPE1; OMA:HSPE1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q33.1 Start 197,500,140 bp[1] End 197,503,449 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C1.2 Start 55,127,291 bp[2] End 55,130,466 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal gland right adrenal cortex left adrenal gland left adrenal cortex mucosa of transverse colon right lobe of liver hypothalamus human kidney ventricular zone C1 segment Top expressed in embryo embryo yolk sac right kidney epiblast blastocyst ventricular zone abdominal wall migratory enteric neural crest cell neural tube More reference expression data BioGPS More reference expression data
Gene ontology Molecular function chaperone binding protein binding ATP binding metal ion binding unfolded protein binding RNA binding Cellular component cytoplasm extracellular exosome membrane mitochondrion mitochondrial matrix Biological process response to unfolded protein activation of cysteine-type endopeptidase activity involved in apoptotic process protein folding osteoblast differentiation chaperone cofactor-dependent protein refolding Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3336 15528 Ensembl ENSG00000115541 ENSMUSG00000073676 UniProt P61604 Q64433 RefSeq (mRNA) NM_002157 NM_008303 RefSeq (protein) NP_002148 NP_032329 Location (UCSC) Chr 2: 197.5 – 197.5 Mb Chr 1: 55.13 – 55.13 Mb PubMed search [3] [4]
Wikidata
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Cpn10
gp31 co-chaperonin from bacteriophage t4
Identifiers
Symbol	Cpn10
Pfam	PF00166
Pfam clan	CL0296
InterPro	IPR020818
PROSITE	PDOC00576
SCOP2	1lep / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Heat shock 10 kDa protein 1 (Hsp10), also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF), is a protein that in humans is encoded by the HSPE1 gene. The homolog in E. coli is GroES that is a chaperonin which usually works in conjunction with GroEL.^[5]