Chinese scientist (born 1984)
He Jiankui ([xɤ̂ tɕjɛ̂nkʰwěɪ] ; Chinese : 贺建奎 ; born 1984) is a Chinese biophysicist who was an associate professor in the Department of Biology of the Southern University of Science and Technology (SUSTech) in Shenzhen , China.[2] [3] [4] Earning his Ph.D. from Rice University in Texas on protein evolution , including that of CRISPR , He learned gene-editing techniques (CRISPR/Cas9 ) as a postdoctoral researcher at Stanford University in California.[5]
In November 2018 he announced that he had created the first human genetically edited babies,[6] [7] twin girls who were born in mid-October 2018 and known by their pseudonyms, Lulu and Nana .[8] [9] [5] [1] The announcement was initially praised in the press as a major scientific advancement.[10] But following scrutiny on how the experiment was executed, He received widespread condemnation.[5] [11] [12] His research activities were suspended by the Chinese authorities on 29 November 2018,[13] and he was fired by SUSTech on 21 January 2019.[14] On 30 December 2019, Chinese court sentenced He to three years of imprisonment and a three-million-yuan fine.[15] He was released from prison in April 2022.[16]
He was listed as one of Time 's 100 most influential people of 2019, in the section "Pioneers".[17] At the same time he was variously referred to as a "rogue scientist",[18] "China's Dr. Frankenstein ",[19] and a "mad genius".[20]
^ a b Bulluck, Pam (14 April 2019). "Gene-Edited Babies: What a Chinese Scientist Told an American Mentor" . The New York Times . Retrieved 14 April 2019 .
^ Cohen, Jon (1 August 2019). "The untold story of the 'circle of trust' behind the world's first gene-edited babies" . Science . doi :10.1126/science.aay9400 . Retrieved 1 August 2019 .
^ "Jiankui He(Nonpaid Leave)- Department of Biology" . bio.sustc.edu.cn . Archived from the original on 2 January 2019. Retrieved 6 December 2018 .
^ Rana, Preetika (10 May 2019). "How a Chinese Scientist Broke the Rules to Create the First Gene-Edited Babies - Dr. He Jiankui, seeking glory for his nation and justice for HIV-positive parents, kept his experiment secret, ignored peers' warnings and faked a test (Paywall)" . The Wall Street Journal . Retrieved 11 May 2019 .
^ a b c Begley, Sharon; Joseph, Andrew (17 December 2018). "The CRISPR shocker: How genome-editing scientist He Jiankui rose from obscurity to stun the world" . Stat News . Retrieved 17 December 2018 .
^ Cite error: The named reference NYT-20190128
was invoked but never defined (see the help page ).
^ "The scientist who created CRISPR babies is on Time's most-influential list—but not in a good way" . MIT Technology Review . 18 April 2019. Retrieved 18 April 2019 .
^ Begley, Sharon (28 November 2018). "Amid uproar, Chinese scientist defends creating gene-edited babies" . STAT News .
^ 复盘贺建奎的人生轨迹:是谁给了他勇气 (in Chinese). sina.com.cn . 27 November 2018. Retrieved 28 November 2018 .
^ Li, Jing-ru; Walker, Simon; Nie, Jing-bao; Zhang, Xin-qing (2019). "Experiments that led to the first gene-edited babies: the ethical failings and the urgent need for better governance" . Journal of Zhejiang University Science B . 20 (1): 32–38. doi :10.1631/jzus.B1800624 . PMC 6331330 . PMID 30614228 .
^ Cite error: The named reference NYT-20181205
was invoked but never defined (see the help page ).
^ Dvorsky, George (30 April 2019). "Substandard, Superficial, and Absurd: Experts Slam the Science Behind the CRISPR Baby Experiment" . Gizmodo . Retrieved 30 April 2019 .
^ Jiang, Steven; Regan, Helen; Berlinger, Joshua (29 November 2018). "China suspends scientists who claim to have produced first gene-edited babies" . CNN News .
^ Cite error: The named reference Reuters-20190121
was invoked but never defined (see the help page ).
^ huaxia. "He Jiankui jailed for illegal human embryo gene-editing" . Xinhuanet . Archived from the original on December 30, 2019. Retrieved 2 January 2020 .
^ "The creator of the CRISPR babies has been released from a Chinese prison" . 2022-04-04.
^ Doudna, Jennifer (18 April 2019). "100 Most Influential People - He Jiankui" . Time . Retrieved 18 April 2019 .
^ Cohen, Jon (2 August 2019). "Inside the circle of trust" . Science . 365 (6452): 430–437. Bibcode :2019Sci...365..430C . doi :10.1126/science.365.6452.430 . PMID 31371593 .
^ Yan, Sophia (28 November 2018). "China's 'Dr Frankenstein' says second woman in early pregnancy with gene-edited babies" . The Telegraph . Retrieved 10 January 2020 .
^ Low, Zoe (27 November 2018). "China's gene editing Frankenstein had dreams of being Chinese Einstein" . South China Morning Post . Retrieved 10 January 2020 .