Back فيروس كورونا البشري HKU1 Arabic Coronavirus humà HKU1 Catalan Human coronavirus HKU1 Danish Humanes Coronavirus HKU1 German Ανθρώπινος κορονοϊός HKU1 Greek Coronavirus humano HKU1 Spanish کروناویروس انسانی اچ‌کی‌یو۱ Persian Ihmisen koronavirus HKU1 Finnish Coronavirus humain HKU1 French HCoV-HKU1 Croatian

Human coronavirus HKU1

Betacoronavirus hongkonense
Formation of HcoV-HKU1.
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Nidovirales
Family: Coronaviridae
Genus: Betacoronavirus
Subgenus: Embecovirus
Species:
Betacoronavirus hongkonense
Synonyms
  • Human coronavirus HKU1
  • HCoV-HKU1

Betacoronavirus hongkonense [1] ( commonly called Human coronavirus HKU1 abbreviated as HCoV-HKU1) is a species of coronavirus in humans and animals. It causes an upper respiratory disease with symptoms of the common cold, but can advance to pneumonia and bronchiolitis.[2] It was first discovered in January 2004 from one man in Hong Kong.[3] Subsequent research revealed it has global distribution and earlier genesis.

The virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor.[4] It has the Hemagglutinin esterase (HE) gene, which distinguishes it as a member of the genus Betacoronavirus and subgenus Embecovirus.[5]

  1. ^ "Taxon Details | ICTV". International Committee on Taxonomy of Viruses (ICTV). Retrieved 25 July 2024.
  2. ^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). "Human Coronaviruses: A Review of Virus–Host Interactions". Diseases. 4 (3): 26. doi:10.3390/diseases4030026. ISSN 2079-9721. PMC 5456285. PMID 28933406. See Table 1.
  3. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).
  4. ^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). "Human Coronaviruses: A Review of Virus–Host Interactions". Diseases. 4 (3): 26. doi:10.3390/diseases4030026. ISSN 2079-9721. PMC 5456285. PMID 28933406. See Table 1.
  5. ^ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. In all members of Betacoronavirus subgroup A, a haemagglutinin esterase (HE) gene, which encodes a glycoprotein with neuraminate O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1).

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