James F. Reed | |
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| Born | James Frazier Reed November 14, 1800 County Armagh, Kingdom of Ireland |
| Died | July 24, 1874 (aged 73) San Jose, California, U.S. |
| Resting place | Oak Hill Cemetery San Jose, California |
| Occupation | Businessman |
| Known for | Donner Party |
| Spouse | Margret Wilson Backenstoe (née Keyes) |
| Children | 6 |
James Frazier Reed (November 14, 1800 – July 24, 1874) was an Irish-American businessman, soldier and pioneer in the American West, notable for being an organizing member of the ill-fated Donner Party emigration to California in 1846.