KCNJ4

KCNJ4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3GJ9
Identifiers
Aliases	KCNJ4, HIR, HIRK2, HRK1, IRK-3, IRK3, Kir2.3, potassium voltage-gated channel subfamily J member 4, potassium inwardly rectifying channel subfamily J member 4
External IDs	OMIM: 600504; MGI: 104743; HomoloGene: 3653; GeneCards: KCNJ4; OMA:KCNJ4 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	38,455,199 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,389,442 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; middle temporal gyrus; ; Brodmann area 10; ; Brodmann area 23; ; frontal pole; ; superior frontal gyrus; ; postcentral gyrus; ; Brodmann area 46; ; Region I of hippocampus proper; ; entorhinal cortex;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; perirhinal cortex; ; dentate gyrus of hippocampal formation granule cell; ; entorhinal cortex; ; prefrontal cortex; ; hippocampus proper; ; nucleus accumbens; ; CA3 field; ; primary motor cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; voltage-gated ion channel activity; PDZ domain binding; inward rectifier potassium channel activity; G-protein activated inward rectifier potassium channel activity;
Cellular component	synapse; cytoplasmic vesicle membrane; voltage-gated potassium channel complex; cell junction; integral component of membrane; membrane; cytoplasmic vesicle; basolateral plasma membrane; postsynaptic membrane; plasma membrane;
Biological process	regulation of ion transmembrane transport; ion transport; potassium ion transport; potassium ion import across plasma membrane; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	3761
	16520
	ENSG00000168135
	ENSMUSG00000044216
	P48050
	P52189
	NM_152868; NM_004981
	NM_008427
	NP_004972; NP_690607
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium inwardly-rectifying channel, subfamily J, member 4, also known as KCNJ4 or K_ir2.3, is a human gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168135 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044216 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: KCNJ4 potassium inwardly-rectifying channel, subfamily J, member 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168135 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044216 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KCNJ4 potassium inwardly-rectifying channel, subfamily J, member 4".

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