Back ثنائي ميثيل نتروزامين Arabic Dimethylnitrosamin German Ν-νιτροσοδιμεθυλαμίνη Greek Dimetilnitrosamina Spanish N-Nitrosodiméthylamine French N-nitrozo-dimetil-amin Hungarian NDMA Italian N-ニトロソジメチルアミン Japanese N-나이트로소다이메틸아민 Korean Dimethylnitrosamine Dutch

N-Nitrosodimethylamine

Not to be confused with MDMA, NMDA, or N-Nitrosodiethylamine.
N-Nitrosodimethylamine
Skeletal formula of N-nitrosodimethylamine
Names
Preferred IUPAC name
N,N-Dimethylnitrous amide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.500 Edit this at Wikidata
EC Number
  • 200-549-8
KEGG
MeSH Dimethylnitrosamine
RTECS number
  • IQ0525000
UNII
UN number 3382
  • InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3 ☒N
    Key: UMFJAHHVKNCGLG-UHFFFAOYSA-N ☒N
  • CN(C)N=O
Properties
C2H6N2O
Molar mass 74.083 g·mol−1
Appearance Yellow oil[1]
Odor faint, characteristic[1]
Density 1.005 g/mL
Boiling point 153.1 °C; 307.5 °F; 426.2 K
290 mg/ml (at 20 °C)
log P −0.496
Vapor pressure 700 Pa (at 20 °C)
1.437
Thermochemistry
1.65 MJ/mol
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Known carcinogen,[1] extremely toxic
GHS labelling:
GHS06: Toxic GHS08: Health hazard GHS09: Environmental hazard
Danger
H300, H330, H350, H372, H411
P260, P273, P284, P301+P310, P310
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 4: Very short exposure could cause death or major residual injury. E.g. VX gasFlammability 2: Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur. Flash point between 38 and 93 °C (100 and 200 °F). E.g. diesel fuelInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
4
2
0
Flash point 61.0 °C (141.8 °F; 334.1 K)
Lethal dose or concentration (LD, LC):
37.0 mg/kg (oral, rat)
NIOSH (US health exposure limits):
PEL (Permissible)
 OSHA-Regulated Carcinogen[1]
REL (Recommended)
 Ca[1]
IDLH (Immediate danger)
 Ca [N.D.][1]
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is an organic compound with the formula (CH3)2NNO. It is one of the simplest members of a large class of nitrosamines. It is a volatile yellow oil. NDMA has attracted wide attention as being highly hepatotoxic and a known carcinogen in laboratory animals.[2]

  1. ^ a b c d e f NIOSH Pocket Guide to Chemical Hazards. "#0461". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ Cite error: The named reference Tricker was invoked but never defined (see the help page).

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