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Oxprenoate potassium

Oxprenoate potassium
Clinical data
Other namesRU-28318; 17α-Hydroxy-3-oxo-7α-propylpregn-4-ene-21-carboxylic acid monopotassium salt
Drug classAntimineralocorticoid
Identifiers
  • potassium 3-[(7R,8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3-oxo-7-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H37KO4
Molar mass440.665 g·mol−1
3D model (JSmol)
  • CCC[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(CCC(=O)[O-])O)C.[K+]
  • InChI=1S/C25H38O4.K/c1-4-5-16-14-17-15-18(26)6-10-23(17,2)19-7-11-24(3)20(22(16)19)8-12-25(24,29)13-9-21(27)28;/h15-16,19-20,22,29H,4-14H2,1-3H3,(H,27,28);/q;+1/p-1/t16-,19+,20+,22-,23+,24+,25-;/m1./s1
  • Key:HXJITUGMCJCKCE-UYOQDFFISA-M

Oxprenoate potassium (developmental code name RU-28318) is a synthetic steroidal antimineralocorticoid which was never marketed.[1] The affinities of oxprenoate potassium for the steroid hormone receptors have been reported.[2]

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 922–. ISBN 978-1-4757-2085-3.
  2. ^ Raynaud JP, Fortin M, Hunt P, Ojasoo T, Doré JC, Surcouf E, Mornon JP, et al. (Fondation Princesse Liliane) (1986). "Approaches to drug development using receptors". In Gotto AM, O'Malley BW (eds.). The Role of Receptors in Biology and Medicine: Proceedings of the Ninth Argenteuil Symposium. Raven Press. pp. 65–77. ISBN 978-0-88167-161-2.

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