P2X purinoceptor 5 is a protein in humans that is encoded by the P2RX5 gene.[5][6]
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Four transcript variants encoding distinct isoforms have been identified for this gene.[6]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000083454 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005950 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Le KT, Paquet M, Nouel D, Babinski K, Seguela P (Jan 1998). "Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system". FEBS Lett. 418 (1–2): 195–9. doi:10.1016/S0014-5793(97)01380-X. PMID 9414125. S2CID 42070561.
- ^ a b "Entrez Gene: P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5".