Pfam

Pfam
Content
DescriptionThe Pfam database provides alignments and hidden Markov models for protein domains.
Data types
captured
Protein families
Organismsall
Contact
Research centerEBI
Primary citationPMID 19920124
Access
Data formatStockholm format
Websitewww.ebi.ac.uk/interpro/entry/pfam/#table
Download URLFTP
Miscellaneous
LicenseGNU Lesser General Public License
Version37.0
Bookmarkable
entities
yes

Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models.[1][2][3] The latest version of Pfam, 37.0, was released in June 2024 and contains 21,979 families.[4] It is currently provided through InterPro website.

  1. ^ Finn RD, Tate J, Mistry J, Coggill PC, Sammut SJ, Hotz HR, Ceric G, Forslund K, Eddy SR, Sonnhammer EL, Bateman A (2008). "The Pfam protein families database". Nucleic Acids Res. 36 (Database issue): D281–8. doi:10.1093/nar/gkm960. PMC 2238907. PMID 18039703.
  2. ^ Finn, R. D.; Mistry, J.; Schuster-Böckler, B.; Griffiths-Jones, S.; Hollich, V.; Lassmann, T.; Moxon, S.; Marshall, M.; Khanna, A.; Durbin, R.; Eddy, S. R.; Sonnhammer, E. L.; Bateman, A. (January 2006). "Pfam: clans, web tools and services" (Free full text). Nucleic Acids Research. 34 (Database issue): D247–D251. doi:10.1093/nar/gkj149. ISSN 0305-1048. PMC 1347511. PMID 16381856.
  3. ^ Bateman, A.; Coin, L.; Durbin, R.; Finn, R. D.; Hollich, V.; Griffiths-Jones, S.; Khanna, A.; Marshall, M.; Moxon, S.; Sonnhammer, E. L.; Studholme, D. J.; Yeats, C.; Eddy, S. R. (2004). "The Pfam protein families database". Nucleic Acids Research. 32 (Database issue): 138D–1141. doi:10.1093/nar/gkh121. ISSN 0305-1048. PMC 308855. PMID 14681378. Open access icon
  4. ^ "Xfam Blog". Xfam Blog. Retrieved 10 September 2024.

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