Port Pirie is a city in South Australia.
Port Pirie may also refer to:
- City of Port Pirie, a former local government area in South Australia
- Electoral district of Port Pirie, a former state electoral district
- Port Pirie Regional Council, a local government area in South Australia
- Port Pirie Post Office, a post office in South Australia
- Port Pirie Airport, airport in South Australia
- Roman Catholic Diocese of Port Pirie, a diocese in South Australia