Odaenathus, the king of Palmyra from 260 to 267 CE, has been identified by modern scholars as the subject of sculptures, seal impressions, and mosaic pieces. His city was part of the Roman Empire, and he came to dominate the Roman East when in 260 he defeated Shapur I, the Sasanian emperor of Persia, who had invaded the Roman Empire. Odaenathus besieged the Sasanian capital Ctesiphon in 263, and although the city did not fall, the campaign led to a full restoration of Roman provinces taken by Shapur I. In the aftermath of his Persian war, Odaenathus assumed the title King of Kings, which was a challenge to the Persian monarch's claims of authority in the region. Odaenathus ruled the Roman East unopposed with imperial consent. In 267, he was assassinated alongside his eldest son Herodianus while conducting a campaign against Germanic raiders in Bithynia; he was succeeded by his son Vaballathus under the regency of the widow queen Zenobia.
Palmyrene portraits were usually abstract, depicting little individuality. Most reported portraits of Odaenathus are undated and have no inscriptions, making identification speculative. Generally, the criteria for determining whether a piece represents the king are its material (imported marble, in contrast to local limestone) and iconography, such as the presence of royal attributes (crowns or diadems). Several limestone head portraits from Palmyra were identified by several twentieth-century scholars as depicting Odaenathus, based on criteria such as the size of the portrait and the presence of a wreath; the latter element was not special in Palmyrene portraits, as priests were also depicted with wreaths. More recent research on the limestone portraits indicates that these pieces were probably funerary objects depicting private citizens.
Two marble heads, both reflecting a high level of individuality, are more likely to be portraits of the king. The first marble sculpture depicts a man in a royal diadem, and the second shows the king in an eastern royal tiara. Two Palmyrene tesserae, depicting a bearded king wearing a diadem and an earring, are also likely to be depictions of Odaenathus, and two mosaic panels have been identified as possibly depicting him: one of them portrays a rider (probably Odaenathus) killing a Chimera, which fits a prophecy in the thirteenth Sibylline Oracle that includes an account contemporary to Odaenathus, prophesying that he will kill Shapur I, who is described as a beast.