Back Alcaloide pirrolizidínic Catalan Pyrrolizidinalkaloide German Pirolizidinaj alkaloidoj Esperanto Alcaloide pirrolizidínico Spanish Alcaloïde pyrrolizidinique French Alkaloid pirrolizidin ID Alcaloide pirrolizidinico Italian ピロリジジンアルカロイド Japanese Пиролизидински алкалоид Macedonian Pyrrolizidine-alkaloïde Dutch

Pyrrolizidine alkaloid

Skeletal formula of retronecine, a pyrrolizidine alkaloid found in the common groundsel (Senecio vulgaris) and comfrey (Symphytum spp.)

Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Their use dates back centuries and is intertwined with the discovery, understanding, and eventual recognition of their toxicity on humans and animals.[1]

  1. ^ Moreira, Rute; Pereira, David M.; Valentão, Patrícia; Andrade, Paula B. (June 2018). "Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety". International Journal of Molecular Sciences. 19 (6): 1668. doi:10.3390/ijms19061668. ISSN 1422-0067. PMC 6032134. PMID 29874826.

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