Radiosynthesis is a fully automated synthesis method in which radioactive compounds are produced.[1] Radiosynthesis is generally carried out by several nuclear interface modules, which are protected by the lead shielding and controlled by a computer semi-automatically. The set-ups of modules are different depending on the type of product and synthesis process. Consequently, the modules should be adapted with the synthesis stages. In some cases, such stages of synthesis are carried out manually in order to optimize the radiochemical yield or due to the incompatibility or lack of module.[2]
- ^ Sugawara, Tohru; Kato, Shinji; Okamoto, Shigeha (1994). "Development of fully-automated synthesis systems". Journal of Automatic Chemistry. 16 (1): 33–42. CiteSeerX 10.1.1.278.1485. doi:10.1155/S1463924694000039. PMC 2548029. PMID 18924982.
- ^ de Vries, Erik F.J; Luurtsema, Gert; Brüssermann, Michael; Elsinga, Philip H; Vaalburg, Willem (1999). "Fully automated synthesis module for the high yield one-pot preparation of 6-[]fluoro-l-DOPA". Applied Radiation and Isotopes. 51 (4): 389–394. doi:10.1016/S0969-8043(99)00057-3.