Back معدل مستقبل انتقائي Arabic 선택적 수용체 조절제 Korean Selektiv reseptormodulator NN Seçici reseptör modülatörü Turkish
| Selective receptor modulator | |
|---|---|
| Drug class | |
 | |
| Class identifiers | |
| Synonyms | SRM |
| Use | Various |
| Biological target | Steroid hormone receptor |
| Chemical class | Steroidal; Nonsteroidal |
| Legal status | |
| In Wikidata | |
In the field of pharmacology, a selective receptor modulator or SRM is a type of drug that has different effects in different tissues.[1] A SRM may behave as an agonist in some tissues while as an antagonist in others. Hence selective receptor modulators are sometimes referred to as tissue selective drugs or mixed agonists / antagonists. This tissue selective behavior is in contrast to many other drugs that behave either as agonists or antagonists regardless of the tissue in question.
- ^ Smith CL, O'Malley BW (February 2004). "Coregulator function: a key to understanding tissue specificity of selective receptor modulators". Endocr. Rev. 25 (1): 45–71. doi:10.1210/er.2003-0023. PMID 14769827.