Sex hormone | |
---|---|
Drug class | |
Class identifiers | |
Synonyms | Sex steroid; Gonadal steroid |
Use | Various |
Biological target | Sex hormone receptors |
Chemical class | Steroidal; Nonsteroidal |
Legal status | |
In Wikidata |
Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors.[1] The sex hormones include the androgens, estrogens, and progestogens. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades.[2] The polypeptide hormones luteinizing hormone, follicle-stimulating hormone and gonadotropin-releasing hormone – each associated with the gonadotropin axis – are usually not regarded as sex hormones, although they play major sex-related roles.