Sodium/glucose cotransporter 2

SLC5A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	7VSI, 7YNK, 7YNJ
Identifiers
Aliases	SLC5A2, SGLT2, solute carrier family 5 member 2
External IDs	OMIM: 182381; MGI: 2181411; HomoloGene: 2289; GeneCards: SLC5A2; OMA:SLC5A2 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	31,490,860 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,871,602 bp
RNA expression pattern
	Top expressed in
	kidney tubule; ; human kidney; ; testicle; ; glomerulus; ; metanephric glomerulus; ; gonad; ; epithelium of colon; ; left testis; ; right testis; ; bone marrow cells;
	Top expressed in
	right kidney; ; human kidney; ; molar; ; mucous cell of stomach; ; supraoptic nucleus; ; ventromedial nucleus; ; crypt of lieberkuhn of small intestine; ; epithelium of small intestine; ; primary motor cortex; ; globus pallidus;
	More reference expression data
	n/a
Gene ontology
Molecular function	low-affinity glucose:sodium symporter activity; symporter activity; transporter activity; glucose:sodium symporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; extracellular exosome; membrane; integral component of plasma membrane;
Biological process	carbohydrate transport; ion transport; glucose transmembrane transport; sodium ion transport; transmembrane transport; hexose transmembrane transport; transport; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	6524
	246787
	ENSG00000140675
	ENSMUSG00000030781
	P31639
	Q923I7
	NM_003041
	NM_133254
	NP_003032
	NP_573517
	Wikidata
View/Edit Human	View/Edit Mouse

The sodium/glucose cotransporter 2 (SGLT2) is a protein that in humans is encoded by the SLC5A2 (solute carrier family 5 (sodium/glucose cotransporter)) gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140675 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030781 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wells RG, Mohandas TK, Hediger MA (September 1993). "Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere". Genomics. 17 (3): 787–789. doi:10.1006/geno.1993.1411. PMID 8244402.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000140675 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030781 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8244402-5] Wells RG, Mohandas TK, Hediger MA (September 1993). "Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere". Genomics. 17 (3): 787–789. doi:10.1006/geno.1993.1411. PMID 8244402.

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