TRPP3

PKD2L2
Identifiers
Aliases	PKD2L2, TRPP5, polycystin 2 like 2, transient receptor potential cation channel
External IDs	OMIM: 604669; MGI: 1858231; HomoloGene: 22812; GeneCards: PKD2L2; OMA:PKD2L2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	137,942,747 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	34,577,169 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; buccal mucosa cell; ; testicle; ; left testis; ; right testis; ; sperm; ; internal globus pallidus; ; gonad; ; muscle of thigh; ; Achilles tendon;
	Top expressed in
	zygote; ; primary oocyte; ; secondary oocyte; ; spermatocyte; ; spermatid; ; granulocyte; ; seminiferous tubule; ; egg cell; ; supraoptic nucleus; ; muscle of thigh;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; calcium channel activity;
Cellular component	integral component of membrane; membrane;
Biological process	ion transport; detection of mechanical stimulus; calcium ion transmembrane transport; biological process;
	Sources:Amigo / QuickGO
Orthologs
	27039
	53871
	ENSG00000078795
	ENSMUSG00000014503
	Q9NZM6
	Q9JLG4
	NM_001258448; NM_001258449; NM_001300921; NM_014386
	NM_001163004; NM_016927
	NP_001245377; NP_001245378; NP_001287850; NP_055201
	NP_001156476; NP_058623
	Wikidata
View/Edit Human	View/Edit Mouse

Polycystic kidney disease 2-like 2 protein (PKD2L2) also known as transient receptor potential polycystic 5 (TRPP5) is a protein that in humans is encoded by the PKD2L2 gene.^[5]

TRPP5 is a member of the transient receptor potential channel family of proteins.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000078795 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000014503 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Veldhuisen B, Spruit L, Dauwerse HG, Breuning MH, Peters DJ (December 1999). "Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)". Eur. J. Hum. Genet. 7 (8): 860–72. doi:10.1038/sj.ejhg.5200383. PMID 10602361.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000078795 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000014503 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10602361-5] Veldhuisen B, Spruit L, Dauwerse HG, Breuning MH, Peters DJ (December 1999). "Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)". Eur. J. Hum. Genet. 7 (8): 860–72. doi:10.1038/sj.ejhg.5200383. PMID 10602361.

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