Tropane alkaloid

Chemical structure of tropane which forms the core of tropane alkaloids
Chemical structure and phylogeny of tropane alkaloids. Displayed are 3 chemical compounds that occur as natural products in 5 plant species

Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure.[1] Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloids such as cocaine and scopolamine are notorious for their psychoactive effects, related usage and cultural associations.[2][3][4][5][6][7] Particular tropane alkaloids such as these have pharmacological properties and can act as anticholinergics or stimulants.

  1. ^ O’Hagan, David (2000). "Pyrrole, pyrrolidine, pyridine, piperidine and tropane alkaloids (1998 to 1999)". Natural Product Reports. 17 (5): 435–446. doi:10.1039/a707613d. PMID 11072891.
  2. ^ Hesse M (2002). Alkaloids: Nature's Curse or Blessing?. Weinheim: Wiley-VCH. p. 304. ISBN 978-3-906390-24-6.
  3. ^ Ryzik M (10 June 2007). "Cocaine: Hidden in Plain Sight". The New York Times. Archived from the original on 11 August 2017. Retrieved 18 May 2017.
  4. ^ "The Buyers – A Social History of America's Most Popular Drugs". FRONTLINE. PBS. Archived from the original on 14 May 2017. Retrieved 18 May 2017.
  5. ^ Anderson L. "Devil's Breath: Urban Legend or the World's Most Scary Drug?". Drugs.com. Retrieved 9 July 2019.
  6. ^ Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.
  7. ^ Rätsch, Christian, The Encyclopedia of Psychoactive Plants: Ethnopharmacology and Its Applications pub. Park Street Press 2005

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