Vascular dementia | |
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Other names | Dementia due to cerebrovascular disease;[1] Vascular cognitive impairment[2] |
Brain atrophy from vascular dementia | |
Specialty | Psychiatry, neurology |
Symptoms | Cognitive impairment, short-term memory loss[3] |
Complications | Heart disease, loss of ability to care for self and interact, pneumonia[4] |
Causes | Conditions that impair blood vessels in the brain and therefore interfere with oxygen delivery to the brain[3] |
Risk factors | High blood pressure, high cholesterol, atrial fibrillation, diabetes[3] |
Diagnostic method | Lab test, neuroimaging test, neuropsychological testing[5] |
Differential diagnosis | Alzheimer’s disease[5] |
Treatment | Symptomatic[3][4] |
Frequency | 15-30% of dementia cases in the United States, Europe, and Asia[5][6] |
Vascular dementia is dementia caused by a series of strokes.[2][4] Restricted blood flow due to strokes reduces oxygen and glucose delivery to the brain, causing cell injury and neurological deficits in the affected region.[6] Subtypes of vascular dementia include subcortical vascular dementia, multi-infarct dementia, stroke-related dementia, and mixed dementia.[2][5]
Subcortical vascular dementia occurs from damage to small blood vessels in the brain. Multi-infarct dementia results from a series of small strokes affecting several brain regions. Stroke-related dementia involving successive small strokes causes a more gradual decline in cognition.[4] Dementia may occur when neurodegenerative and cerebrovascular pathologies are mixed, as in susceptible elderly people (75 years and older).[2][5] Cognitive decline can be traced back to occurrence of successive strokes.[4]
ICD-11 lists vascular dementia as dementia due to cerebrovascular disease.[1] DSM-5 lists vascular dementia as either major or mild vascular neurocognitive disorder.[7]