If you have default settings on Wikipedia, and are reading this page on a screen, then you probably can't read the following:
because it has blue text on a blue background.
Text that you probably can read, such as red on green, may present a similar problem to people who have colour-blindness.
Text with low contrast, such as light grey on dark grey, presents a similar problem to people with other eyesight-related conditions.
The more severe their condition, the higher the contrast has to be for them to be able to read it.
The non-discrimination policy is "approved by the Wikimedia Foundation Board of Trustees to apply to all Wikimedia projects. It may not be circumvented, eroded, or ignored by local policies."
It says: "The Wikimedia Foundation prohibits discrimination against current or prospective users... on the basis of... disability"
.
To avoid these problems, you should ensure that text meets the guidelines set out in WP:COLOUR.