Luzerne County is a county in the U.S. state of Pennsylvania. As of the 2020 census, the population was 325,594,[1] making it the most populous county in the northeastern part of the state.
The county seat and largest city is Wilkes-Barre.[2]
Other populous communities include Hazleton, Kingston, Nanticoke, and Pittston. Luzerne County is included in the Scranton–Wilkes-Barre Metropolitan Statistical Area, which has a total population of 567,559 (as of 2020).